Session : The Gut Microbiota and Personalized Nutrition

Session Overview

Join us in this session dedicated to microbiota and personalized nutrition, where renowned professors and students will show you the importance of specific strategies such as targeted diets and supplements adapted to different stages of life, whether in childhood or in an inflammatory context. To round things off, we’ll have a discussion with experts from the food and health industry to explore all these strategies, including the regulatory aspects, marketing, interest and concrete impact on consumers.

Room 202

Chair : Vincenzo Di Marzo – Université Laval
Co-Chair : Charlène Roussel – Université Laval
Sponsors : UMI-MicroMeNu and BioK+ Kerry

1:30 PM - 2:10 PM


New Nutritional Strategies Against Colonic Inflammation From the Gut Microbiome

Read the summary

Abstract to come.

2:10 PM - 2:35 PM


The Mediterranean Diet as a Manner to Modify the Host Metabolome and Gut Microbiome

Read the summary

Our dietary choices have a direct impact on our gut microbiota, which in turn plays a crucial role in influencing our overall health. This intricate interplay between diet, the microbiota, and the human body hinges on the exchange and alteration of metabolites. We seek to understand several key aspects of this relationship: What is the impact of diet on the microbiota and the circulating metabolome? Over what specific timeframes do these dynamic interactions occur? And how do the effects on both the microbiome and the metabolome compare between the typical Canadian diet and a diet inspired by the Mediterranean region?

2:35 PM - 3:00 PM


Probiotics and Infant Nutrition

Read the summary

The effects of probiotics on premature infants are not well understood. In a randomized intervention trial, we show that a multi-strain probiotic mix accelerated microbiome maturation to resemble that of full-term infants and improved the metabolic and immune parameters, highlighting the critical ecological role of these species in the early life microbiome. 

3:00 PM - 3:30 PM

30-Minute Break

3:30 PM - 3:42 PM


Ability of the Probiotic Strain Weizmannia coagulans BC30 to Increase Amino Acids Uptake

Read the summary

71% of consumers globally believe microbial cultures or probiotics have a positive impact on health. Digestive health is the most common health area that consumers are looking to address when taking probiotics but as science and technology progresses, our understanding of probiotics and their wide range of health benefits also expands. Weizmannia (Bacillus) coagulans GBI-30, 6086 (BC30) is a spore-forming, patented probiotic ingredient that can be formulated into almost any food, beverage or companion animal product. It is a highly stable probiotic with the ability to survive harsh manufacturing processes, product shelf-life and the journey through the digestive system. The strain is supported by more than 45 published research papers confirming it’s safety, efficacy and ability to support health benefits such as digestive health, immune health and protein absorption. During this presentation, you will learn more about BC30 with a deep dive into the science behind its digestive and protein absorption scientific research.

3:42 PM - 3:55 PM


Circulating Metabolites Response to Short-term Dietary Interventions in Humans

Read the summary

Introduction : The contribution of diet to metabolic health is well recognized, but a new player is also thought to have an important effect: the gut microbiota. Since its composition depends on the host’s diet and metabolism, metabolic health is not determined by specific factors, but by a complex network of interactions between diet, microbiota and metabolism. The aim of this project is to gain a better understanding of this trialogue.

Method : In a longitudinal study, 21 participants received a Mediterranean diet (MedDiet) for 3 days, a 13-day lead-in controlled diet reflecting the average Canadian dietary intake (CanDiet), and once again a MedDiet for 3 consecutive days. Fecal and blood samples were taken at each change of diet in the protocol for analysis.

Results : On the 1261 circulating metabolites detected, 92 exhibited an immediate and reversible response to the dietary intervention, while 55 metabolites displayed non-reversible changes after 3 days of MedDiet following CanDiet. Functional analysis using the KEGG database revealed the significant impact of dietary interventions, primarily on the histidine metabolic pathway. Interestingly, certain metabolites showed interindividual variation, suggesting significant differences among participants. Furthermore, out of the 64 bacterial genera comprising over 1% of the gut microbiota, 56 genera exhibited strong correlations with an average of 5 metabolites each. Using a random forest algorithm, we successfully differentiated dietary interventions by metabolites that are modulated by diet. Moreover, this same algorithm applied to the visit preceding the study distinguishes participants according to their dietary habits, primarily by their consumption of saturated, unsaturated and total fatty acids.

Conclusion : This study highlights the importance of considering diet in studies looking at the relationship between gut microbiota and metabolism. Moreover, metabolic profile analysis must consider the uniqueness of metabolites.

3:55 PM - 4:30 PM


Impact of Pre-, Pro- and Synbiotics and Fermented Foods on the Gut Microbiome and Their Role in Personalised Medicine

Moderator : Charlène Roussel

Read the summary

How to introduce new food products (e.g., probiotics, fermented foods, etc.) that can impact the microbiota and digestive health, as well as the challenges surrounding personalized nutrition (where are we, what is the evidence, new tools in nutrigenetics, epigenetics, bioinformatics, etc., and perspectives).


Explore the sessions encompassing a wide range of current topics!